GM-CSF (18-141) (recombinant) - AR50017PU-N

Product Description for GM-CSF

GM-CSF.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	CSF2, Colony stimulating factor 2, GMCSF, Granulocyte-macrophage colony-stimulating factor, Molgramostin, Sargramostim
Presentation	Purified
Molecular weight	14 kDa
Source	E. coli
Species (Protein)	Mouse
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P01587
Purity	> 95 % by SDS - PAGE
Background	GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. Mouse GM-CSF protein is 125 amino acids and shares approximately 60% homology with the human GM-CSF protein. Recombinant mouse GM-CSF was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Fleetwood AJ., et al , (2005). Crit Rev Immunol. 25(5):405-28.Hamilton JA., et al. (2004). Growth Factors. 22(4):225-31.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	AA Sequence: `MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK` Molecular weight: (125 aa), confirmed by MALDI-TOF.
Format	Buffer System: Phosphate -buffered saline (PBS), pH 7.4, 10% glycerol Purity: >95% by SDS - PAGE State: Liquid purified protein Purified