AR50480PU-S RBBP4 / RBAP48 (1-425, His-tag)

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0.1 mg / €320.00
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RBBP4 / RBAP48

Product Description for RBBP4 / RBAP48

RBBP4 / RBAP48.
Presentation: Purified

Properties for RBBP4 / RBAP48

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms CAF-1 subunit C, CAF-I p48, Chromatin assembly factor 1 subunit C, Chromatin assembly factor I p48 subunit, Histone-binding protein RBBP4, Nucleosome-remodeling factor subunit RBAP48, RBBP-4, Retinoblastoma-binding protein 4, Retinoblastoma-binding protein p48
Presentation Purified
Molecular weight 50.2 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q09028
Purity > 90 % by SDS - PAGE
Background Retinoblastoma binding protein 4, also known as RBBP4, is a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. RBBP4 is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Qian YW., et al. (1993) Nature. 364(6438): 648-52Nicolas E., et al. (2001) Nucleic Acids Res. 29(15): 3131-6.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human RBBP4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMADKEA AFDDAVEERV INEEYKIWKK NTPFLYDLVM THALEWPSLT AQWLPDVTRP EGKDFSIHRL VLGTHTSDEQ NHLVIASVQL PNDDAQFDAS HYDSEKGEFG GFGSVSGKIE IEIKINHEGE VNRARYMPQN PCIIATKTPS SDVLVFDYTK HPSKPDPSGE CNPDLRLRGH QKEGYGLSWN PNLSGHLLSA SDDHTICLWD ISAVPKEGKV VDAKTIFTGH TAVVEDVSWH LLHESLFGSV ADDQKLMIWD TRSNNTSKPS HSVDAHTAEV NCLSFNPYSE FILATGSADK TVALWDLRNL KLKLHSFESH KDEIFQVQWS PHNETILASS GTDRRLNVWD LSKIGEEQSP EDAEDGPPEL LFIHGGHTAK ISDFSWNPNE PWVICSVSED NIMQVWQMAE NIYNDEDPEG SVDPEGQGS
Molecular weight:
(449aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM EDTA
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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