Product Description for PHOSPHO2
PHOSPHO2.
Presentation: Purified
Presentation: Purified
Properties for PHOSPHO2
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 50 µg |
| Synonyms | Phosphatase orphan 2, Pyridoxal phosphate phosphatase PHOSPHO2 |
| Presentation | Purified |
| Molecular weight | 30.3 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 85 % by SDS - PAGE |
| Background | Pyridoxal phosphate phosphatase PHOSPHO2, orphan 2, also known as PHOSPHO2, belongs to the haloacid dehalogenase(HAD) superfamily. Phosphatase has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). PHOSPHO 1, a phosphoethanolamine/phosphocholine phosphatase, is upregulated in mineralising cells and is thought to be involved in the generation of inorganic phosphate for bone mineralization. PHOSPHO2 is a putative phosphatase sharing 42% sequence identity with PHOSPHO1. PHOSPHO1 and PHOSPHO2 are very similar, but surprisingly, recombinant PHOSPHO2 hydrolyses phosphoethanolamine and phosphocholine relatively poorly. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Roberts SJ., et al. (2005) Biochim Biophys Acta. 1752(1):73-82.Stewart A J., et al. (2003) Protein Eng. 16(12):889-95. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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