Product Description for Tropomyosin-3 (TPM3)
Tropomyosin-3 (TPM3).
Presentation: Purified
Presentation: Purified
Properties for Tropomyosin-3 (TPM3)
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | Gamma-tropomyosin, TPM5, Tropomyosin alpha-3 chain, Tropomyosin-5 |
| Presentation | Purified |
| Molecular weight | 31.6 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 90 % by SDS - PAGE |
| Background | Tropomyosin alpha-3 chain, also known as TPM3, is member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Ohtsuki I., et al. (2002) J Biochem. 131:739-743.Tiso N., et al. (1997) Biochem Biophys Res Commun. 230:347-350. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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