Product Description for Inhibin alpha / INHA
Inhibin alpha / INHA.
Presentation: Purified
Presentation: Purified
Properties for Inhibin alpha / INHA
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Presentation | Purified |
| Molecular weight | 17.0 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | INHA, also known as Inhibin alpha, belongs to the TGF-beta family. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Knight, P.G. (1996) Front. Neuroendocrinol. 17: 476-509.Mather, J.P., et al. (1997). Proc. Soc. Exp. Biol. Med. 215: 209-222. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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