FRZB / SFRP3 (33-325, His-tag) - AR50712PU-N

Product Description for FRZB / SFRP3

FRZB / SFRP3.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	FIZ, FRE, FRP, FRZB1, Frezzled, Fritz, Frizzled-related protein 1, FrzB-1, Secreted frizzled-related protein 3
Presentation	Purified
Molecular weight	35 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q92765
Purity	> 90 % by SDS - PAGE
Background	FRZB is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Baker-Lepain JC, Lynch JA, et al. (2012). Arthritis Rheum. 64(5):1457-65. Ekström EJ, Sherwood V, et al. (2011). PLoS One. 6(4):e18674.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human FRZB protein, fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSAACEPVR IPLCKSLPWN MTKMPNHLHH STQANAILAI EQFEGLLGTH CSPDLLFFLC AMYAPICTID FQHEPIKPCK SVCERARQGC EPILIKYRHS WPENLACEEL PVYDRGVCIS PEAIVTADGA DFPMDSSNGN CRGASSERCK CKPIRATQKT YFRNNYNYVI RAKVKEIKTK CHDVTAVVEV KEILKSSLVN IPRDTVNLYT SSGCLCPPLN VNEEYIIMGY EDEERSRLLL VEGSIAEKWK DRLGKKVKRW DMKLRHLGLS KSDSSNSDST QSQKSGRNSN PRQARN` Molecular weight: (316aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol Purity: >90% by SDS - PAGE State: Liquid purified protein Purified