Product Description for CDK2AP2
CDK2AP2.
Presentation: Purified
Presentation: Purified
Properties for CDK2AP2
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | CDK2-associated protein 2, Cyclin-dependent kinase 2-associated protein 2, DOC-1-related protein, DOC1R |
| Presentation | Purified |
| Molecular weight | 15.5 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 95 % by SDS - PAGE |
| Background | CDK2AP2, also known as DOC-1R and p14, belongs to the CDK2AP family. CDK2-associated protein is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. CDK2AP2 is a regulator for self-renewal of mouse embryonic stem cells (mESCs) under permissive conditions, and cell survival during differentiation of the mESCs into terminally differentiated cell types. CDK2AP2 may be involved in the regulation of self-renewal of stem cells during early embryogenesis. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Deshpande AM, et al. (2012) Stem Cells Dev. Jun 25.Shintani, et al. (2000) Mol. Cell. Biol. (UNITED STATES) 20 (17): 6300–7. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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