SPINT2 / HAI2 (28-197, His-tag) - AR50647PU-S

Product Description for SPINT2 / HAI2

SPINT2 / HAI2.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	50 µg
Synonyms	HAI-2, Hepatocyte growth factor activator inhibitor type 2, Kunitz-type protease inhibitor 2, Placental bikunin
Presentation	Purified
Molecular weight	21.8 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: O43291
Purity	: > 85% by SDS - PAGE
Background	SPINT2 is a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This protein is a putative tumor suppressor, and mutations in this protein result in congenital sodium diarrhea.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Bergum,C.et al. (2010) Prostate 70 (13), 1422-1428 Huang,H.P.,et al. (2012) Hepatology 55 (1), 161-172
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human SPINT2 protein, fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSHMADRER SIHDFCLVSK VVGRCRASMP RWWYNVTDGS CQLFVYGGCD GNSNNYLTKE ECLKKCATVT ENATGDLATS RNAADSSVPS APRRQDSEDH SSDMFNYEEY CTANAVTGPC RASFPRWYFD VERNSCNNFI YGGCRGNKNS YRSEEACMLR CFRQQENPPL PLGSK` Molecular weight: (195aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea 10% glycerol Purity: : > 85% by SDS - PAGE State: Liquid purified protein Purified