AR50649PU-N LIN7B (1-207, His-tag)

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0.25 mg / €820.00
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Quick Overview

LIN7B

Product Description for LIN7B

LIN7B.
Presentation: Purified

Properties for LIN7B

Product Category Proteins & Growth Factors
Quantity 0.25 mg
Synonyms LIN7B, Lin-7 homolog B, Lin-7B, MALS-2, MALS2, Mammalian lin-seven protein 2, VELI2, Veli-2 protein, Vertebrate lin-7 homolog 2, hLin7B, hVeli2
Presentation Purified
Molecular weight 25.3 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9HAP6
Purity > 90 % by SDS - PAGE
Background LIN7B, also known as VELI2, belongs to the Velis family. Velis are a family of small synaptic proteins that interact with other proteins at the post-synaptic density (PSD) of neuronal synapses. Velis contain the PDZ motif involved in recruiting cell adhesion molecules, receptors, and channels. Lin7B is ubiquitously expressed with high expression in brain, liver, and testis. It localized at the synaptic junctions in neurons. Lin7B bind to CASK, a neurexin-binding protein highly concentrated in synapses, and Mint1, a binding partner with a vesicle trafficking protein.
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings Okamoto M., et al. (1997) J Biol Chem. 272:31459-31464-293Irie M., et al. (1999) Oncogene. 18:2811-2817.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human LIN7B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMAALVEP LGLERDVSRA VELLERLQRS GELPPQKLQA LQRVLQSRFC SAIREVYEQL YDTLDITGSA EIRAHATAKA TVAAFTASEG HAHPRVVELP KTDEGLGFNI MGGKEQNSPI YISRVIPGGV ADRHGGLKRG DQLLSVNGVS VEGEQHEKAV ELLKAAQGSV KLVVRYTPRV LEEMEARFEK MRSARRRQQH QSYSSLESRG
Molecular weight:
(230aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol,2mM DTT
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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