Product Description for MRPL28
MRPL28.
Presentation: Purified
Presentation: Purified
Properties for MRPL28
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 50 µg |
| Synonyms | 39S ribosomal protein L28, L28mt, MAAT1, MRP-L28, Melanoma antigen p15, Melanoma-associated antigen recognized by T lymphocytes, mitochondrial |
| Presentation | Purified |
| Molecular weight | 25.8 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 95 % by SDS - PAGE |
| Background | MRPL28, also as known as 39S ribosomal protein L28, mitochondrial, is a mitochondrial protein that belongs to the ribosomal protein L28P family. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPL28 potentially represents an important therapeutic reagent for HLA-A24 (A24) patients as this antigen is recognized by tumor-infiltrating lymphocyte (TIL) 1290, which targets the A24 serotype. This protein is found in a variety of normal tissues including spleen, testis, thymus, liver, kidney, brain, adrenal, lung and retinal tissue. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Koc EC, et al. (2001) J Biol Chem 276 (47): 43958–69.Kawakami, Y., et al. (2000) J.Immunother. 23: 17-27. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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