Product Description for PHF11
PHF11.
Presentation: Purified
Presentation: Purified
Properties for PHF11
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | APY, BCAP, BRCA1 C-terminus-associated protein, IGEL, IGER, IGHER, NY-REN-34, PHD finger protein 11, Renal carcinoma antigen NY-REN-34 |
| Presentation | Purified |
| Molecular weight | 39.7 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | PHD finger protein 11, also known as PHF11, is a regulator of TH1-type cytokine gene expression. The reduction in PHF11 expression seen with an AD-associated genotype could contribute to the strong TH2 responses that characterize many allergic individuals. PHF11 are associated with increased total serum IgE levels, asthma, and severe atopic dermatitis (AD) in children. Although PHF11 includes a plant homeodomain, a motif often found in transcriptional regulators, the function of PHF11 has not been investigated. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Clarke E., et al. (2008) J. Allergy Clin. Immunol. 121:1148-1154Scanlan M.J., et al. (1999) Int. J. Cancer. 83:456-464 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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