Fast skeletal muscle Troponin I (1-182, His-tag) - AR50634PU-S

Product Description for Fast skeletal muscle Troponin I

Fast skeletal muscle Troponin I.
Presentation: Purified

Immunogen	Swiss Prot Num: P48788
Purity	> 90 % by SDS - PAGE
Background	Troponin I, fast skeletal muscle, also known as TNNI2, is a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in TNNI2 cause myopathy and distal arthrogryposis type 2B.
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Ausoni S., et al. (1994) J Biol Chem. 269:339-346.Potter J D., et al. (1995) J Biol Chem. 270:2557-2562.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human TNNI2 protein, fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGDEEKRNRA ITARRQHLKS VMLQIAATEL EKEESRREAE KQNYLAEHCP PLHIPGSMSE VQELCKQLHA KIDAAEEEKY DMEVRVQKTS KELEDMNQKL FDLRGKFKRP PLRRVRMSAD AMLKALLGSK HKVCMDLRAN LKQVKKEDTE KERDLRDVGD WRKNIEEKSG MEGRKKMFES ES` Molecular weight: (202aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 2M Urea, 20% glycerol, 0.2M NaCl Purity: >90% by SDS - PAGE State: Liquid purified protein Purified