GINS4 / SLD5 (1-223, His-tag) - AR50616PU-S

Product Description for GINS4 / SLD5

GINS4 / SLD5.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	20 µg
Synonyms	DNA replication complex GINS protein SLD5, GINS complex subunit 4
Presentation	Purified
Molecular weight	28.2 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9BRT9
Purity	> 90 % by SDS - PAGE
Background	GINS4 plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Kamada K., et al. (2007) Nat. Struct. Mol. Biol. 14:388-396Chang Y.P., et al. (2007) Proc. Natl. Acad. Sci. U.S.A. 104:12685-12690
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human GINS4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MTEEVDFLGQ DSDGGSEEVV LTPAELIERL EQAWMNEKFA PELLESKPEI VECVMEQLEH MEENLRRAKR EDLKVSIHQM EMERIRYVLS SYLRCRLMKI EKFFPHVLEK EKTRPEGEPS SLSPEELAFA REFMANTESY LKNVALKHMP PNLQKVDLFR AVPKPDLDSY VFLRVRERQE NILVEPDTDE QRDYVIDLEK GSQHLIRYKT IAPLVASGAV QLI` Molecular weight: (243aa) confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 1mM DTT Purity: >90% by SDS - PAGE State: Liquid purified protein Purified