AR50590PU-N KLK1 / Kallikrein-1 (25-262, His-tag)

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0.1 mg / €820.00
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KLK1 / Kallikrein-1

Product Description for KLK1 / Kallikrein-1

KLK1 / Kallikrein-1.
Presentation: Purified

Properties for KLK1 / Kallikrein-1

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms EC 3.4.21.35, KLK-1, Kallikrein1, Kidney/pancreas/salivary gland kallikrein, Tissue kallikrein
Presentation Purified
Molecular weight 28.7 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P06870
Purity > 90 % by SDS - PAGE
Background Kallikrein-1, also known as KLK1, belongs to the Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings Lu H.S., et al. (1989) Int. J. Pept. Protein Res. 33:237-249Kellermann J., et al. (1988) Protein Seq. Data Anal. 1:177-182
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human KLK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MIVGGWECEQ HSQPWQAALY HFSTFQCGGI LVHRQWVLTA AHCISDNYQL WLGRHNLFDD ENTAQFVHVS ESFPHPGFNM SLLENHTRQA DEDYSHDLML LRLTEPADTI TDAVKVVELP TQEPEVGSTC LASGWGSIEP ENFSFPDDLQ CVDLKILPND ECKKVHVQKV TDFMLCVGHL EGGKDTCVGD SGGPLMCDGV LQGVTSWGYV PCGTPNKPSV AVRVLSYVKW IEDTIAENS
Molecular weight:
(259aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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