Product Description for KLK7 / Kallikrein-7
KLK7 / Kallikrein-7.
Presentation: Purified
Presentation: Purified
Properties for KLK7 / Kallikrein-7
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | PRSS6, SCCE, Serine protease 6, Stratum corneum chymotryptic enzyme, hK7 |
| Presentation | Purified |
| Molecular weight | 27.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 90 % by SDS - PAGE |
| Background | KLK7 is a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikreins are biomarkers for cancer. The protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. KLK7 may play a role in cancer invasion and metastasis, and increased expression of this protein is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Talieri,M.,et al. (2011) Anticancer Res. 31 (9), 3093-3100Ramani,V.C., et al. (2011) Biochim. Biophys. Acta 1813 (8), 1525-1531 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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