Product Description for ABI3
ABI3.
Presentation: Purified
Presentation: Purified
Properties for ABI3
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 20 µg |
| Synonyms | ABI gene family member 3, NESH |
| Presentation | Purified |
| Molecular weight | 41.4 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | ABI3, also as known as ABI gene family member 3, belongs to the ABI family. This protein is a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain. The Abi family members are thought to negatively regulate cell growth and transformation, including cellular transformation through v-Abl as well as mediate cell motility by regulating actin polymerization in lamellipodia and filopodia. ABI3 inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Ichigotani Y., et al. (2002) Cancer Res. 62:2215-2219Miyazaki K, et al. (2000) Biochim Biophys Acta 1493 (1-2): 237–41. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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