Product Description for HAND1 / EHAND
HAND1 / EHAND.
Presentation: Purified
Presentation: Purified
Properties for HAND1 / EHAND
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | BHLHA27, Class A basic helix-loop-helix protein 27, Extraembryonic tissues heart autonomic nervous system and neural crest derivatives-expressed protein 1, Heart- and neural crest derivatives-expressed protein 1 |
| Presentation | Purified |
| Molecular weight | 26 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 90 % by SDS - PAGE |
| Background | HAND1 belongs to the basic helix-loop-helix family of transcription factors. This protein is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Scott IC., et al. (2000). Mol Cell Biol. 20(2):530-41.Srivastava D. Trends Cardiovasc Med. 1999 Jan-Feb;9(1-2):11-8. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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