AR50563PU-S HAND1 / EHAND (1-215, His-tag)

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0.1 mg / €320.00
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HAND1 / EHAND

Product Description for HAND1 / EHAND

HAND1 / EHAND.
Presentation: Purified

Properties for HAND1 / EHAND

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms BHLHA27, Class A basic helix-loop-helix protein 27, Extraembryonic tissues heart autonomic nervous system and neural crest derivatives-expressed protein 1, Heart- and neural crest derivatives-expressed protein 1
Presentation Purified
Molecular weight 26 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O96004
Purity > 90 % by SDS - PAGE
Background HAND1 belongs to the basic helix-loop-helix family of transcription factors. This protein is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Scott IC., et al. (2000). Mol Cell Biol. 20(2):530-41.Srivastava D. Trends Cardiovasc Med. 1999 Jan-Feb;9(1-2):11-8.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human HAND1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMNLVGSY AHHHHHHHPH PAHPMLHEPF LFGPASRCHQ ERPYFQSWLL SPADAAPDFP AGGPPPAAAA AATAYGPDAR PGQSPGRLEA LGGRLGRRKG SGPKKERRRT ESINSAFAEL RECIPNVPAD TKLSKIKTLR LATSYIAYLM DVLAKDAQSG DPEAFKAELK KADGGRESKR KRELQQHEGF PPALGPVEKR IKGRTGWPQQ VWALELNQ
Molecular weight:
(238aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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