NDUFA2 (1-99, His-tag) - AR50594PU-N

Product Description for NDUFA2

NDUFA2.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.25 mg
Synonyms	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
Presentation	Purified
Molecular weight	13.3 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: O43678
Purity	> 95 % by SDS - PAGE
Background	NDUFA2 is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox. Mutations in this protein are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Murray,J.,et al. (2003) J. Biol. Chem. 278 (16), 13619-13622Loeffen,J.L.., et al. (1998) Biochem. Biophys. Res. Commun. 253 (2), 415-422.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human NDUFA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMAAAAAS RGVGAKLGLR EIRIHLCQRS PGSQGVRDFI EKRYVELKKA NPDLPILIRE CSDVQPKLWA RYAFGQETNV PLNNFSADQV TRALENVLSG KA` Molecular weight: (122aa) confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol,1mM DTT Purity: >95% by SDS - PAGE State: Liquid purified protein Purified