Product Description for CHMP5
CHMP5.
Presentation: Purified
Presentation: Purified
Properties for CHMP5
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 50 µg |
| Synonyms | C9orf83, CHMP-5, Charged multivesicular body protein 5, Chromatin-modifying protein 5, SNF7 domain-containing protein 2, SNF7DC2, Vacuolar protein-sorting-associated protein 60, Vps60, hVps60 |
| Presentation | Purified |
| Molecular weight | 27 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 80 % by SDS - PAGE |
| Background | CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Howard TL, Stauffer DR, et al. (2001). J Cell Sci. 2395-404.Ward DM, Vaughn MB, et al. (2005). J Biol Chem. 18;280(11):10548-55. Epub 2005 Jan 11. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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