Product Description for XAB1
XAB1.
Presentation: Purified
Presentation: Purified
Properties for XAB1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | ATPBD1A, GPN1, GTPase, MBDIN, NTPBP, XPA binding protein 1 |
| Presentation | Purified |
| Molecular weight | 44.3 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | XAB1, as known as GPN1, belongs to the GPN-loop GTPase family. Small GTPases share a biochemical mechanism and act as binary molecular switches. One important function of small GTPases in the cell is nucleocytoplasmic transport of both proteins and RNA. This protein may play a role in DNA repair and may function in activation of transcription. And it forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. |
| Concentration | 1mg/ml (determined by Bradford assay) |
| General Readings | Carre C, et al. (2011) Mol Cell Biol. 31(19):3953-62.Forget D, et al. (2010) Mol Cell Proteomics. 9(12):2827-39. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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