Product Description for RGS14
RGS14.
Presentation: Purified
Presentation: Purified
Properties for RGS14
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 20 µg |
| Synonyms | Regulator of G-protein signaling 14 |
| Presentation | Purified |
| Molecular weight | 63.6 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 80 % by SDS - PAGE |
| Background | RGS14 (Regulator of G-protein signaling 14) belongs to regulator of G protein signalling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco motif. RGS14 is highly enriched in CA2 pyramidal neurons and plays a role in suppression of both synaptic plasticity at these synapses and hippocampal-based learning and memory. RGS14 is a scaffolding protein that integrates G protein and H-Ras/ERK/MAP kinase signaling pathways, thereby making it well positioned to suppress plasticity in CA2 neurons. |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| General Readings | Lee SE, et al. (2010) Proc Natl Acad Sci U S A. 107(39):16994-8.Martin-McCaffrey L., et al. (2005) Cell Cycle 4:953-960 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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