Product Description for TCEAL7
TCEAL7.
Presentation: Purified
Presentation: Purified
Properties for TCEAL7
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | TCEA-like protein 7, Transcription elongation factor A protein-like 7, Transcription elongation factor S-II protein-like 7 |
| Presentation | Purified |
| Molecular weight | 14.8 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 80 % by SDS - PAGE |
| Background | TCEAL7 plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. It associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. This protein regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres) and telomerase-positive cell lines. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Lafferty-Whyte,K., et al. (2010) Neoplasia 12 (5), 405-414Rattan,R., et al. (2010) Oncogene 29 (9), 1362-1373 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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