AR50440PU-S TCEAL7 (1-100, His-tag)

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0.1 mg / €320.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

TCEAL7

Product Description for TCEAL7

TCEAL7.
Presentation: Purified

Properties for TCEAL7

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms TCEA-like protein 7, Transcription elongation factor A protein-like 7, Transcription elongation factor S-II protein-like 7
Presentation Purified
Molecular weight 14.8 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9BRU2
Purity > 80 % by SDS - PAGE
Background TCEAL7 plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. It associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. This protein regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres) and telomerase-positive cell lines.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Lafferty-Whyte,K., et al. (2010) Neoplasia 12 (5), 405-414Rattan,R., et al. (2010) Oncogene 29 (9), 1362-1373
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human TCEAL7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMQKPCK ENEGKPKCSV PKREEKRPYG EFERQQTEGN FRQRLLQSLE EFKEDIDYRH FKDEEMTREG DEMERCLEEI RGLRKKFRAL HSNHRHSRDR PYPI
Molecular weight:
(124aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 0.2M NaCl, 2mM DTT
Purity:
>80% by SDS - PAGE
State:
Liquid purified protein
Purified
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