Product Description for CHMP1B
CHMP1B.
Presentation: Purified
Presentation: Purified
Properties for CHMP1B
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | C18orf2, CHMP1.5, Charged multivesicular body protein 1b, Chromatin-modifying protein 1b |
| Presentation | Purified |
| Molecular weight | 24.7 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | CHMP1B, also known as charged multivesicular body protein 1b, is probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. |
| Concentration | 0.25mg/ml (determined by Bradford assay) |
| General Readings | Martin-Serrano J., et al. (2003) Proc. Natl. Acad. Sci. U.S.A. 100:12414-12419Bajorek M., et al. (2009) Mol. Biol. Cell. 20:1360-1373 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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