Product Description for MEMO1
MEMO1.
Presentation: Purified
Presentation: Purified
Properties for MEMO1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | C21orf19-like protein, C2orf4, CGI-27, HCV NS5A-transactivated protein 7, Hepatitis C virus NS5A-transactivated protein 7, Mediator of ErbB2-driven cell motility 1, NS5ATP7 |
| Presentation | Purified |
| Molecular weight | 36.4 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 95 % by SDS - PAGE |
| Background | MEMO1 (Mediator of ErbB2-driven cell motility 1), also known as C2orf4 or NS5ATP7, belongs to the UPF0103 family. MEMO1 control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. It is required for breast carcinoma cell migration, suggesting an important role in tumorigenesis. Also, it controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| General Readings | Marone R., et al. (2004) Nat. Cell Biol. 6:515-522Zaoui K., et al. (2010) Proc. Natl. Acad. Sci. U.S.A. 107:18517-18522 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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