AR50443PU-N MEMO1 (1-297, His-tag)

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0.5 mg / €820.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

MEMO1

Product Description for MEMO1

MEMO1.
Presentation: Purified

Properties for MEMO1

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms C21orf19-like protein, C2orf4, CGI-27, HCV NS5A-transactivated protein 7, Hepatitis C virus NS5A-transactivated protein 7, Mediator of ErbB2-driven cell motility 1, NS5ATP7
Presentation Purified
Molecular weight 36.4 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y316
Purity > 95 % by SDS - PAGE
Background MEMO1 (Mediator of ErbB2-driven cell motility 1), also known as C2orf4 or NS5ATP7, belongs to the UPF0103 family. MEMO1 control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. It is required for breast carcinoma cell migration, suggesting an important role in tumorigenesis. Also, it controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity.
Concentration 0.5mg/ml (determined by Bradford assay)
General Readings Marone R., et al. (2004) Nat. Cell Biol. 6:515-522Zaoui K., et al. (2010) Proc. Natl. Acad. Sci. U.S.A. 107:18517-18522
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human MEMO1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMMSNRV VCREASHAGS WYTASGPQLN AQLEGWLSQV QSTKRPARAI IAPHAGYTYC GSCAAHAYKQ VDPSITRRIF ILGPSHHVPL SRCALSSVDI YRTPLYDLRI DQKIYGELWK TGMFERMSLQ TDEDEHSIEM HLPYTAKAME SHKDEFTIIP VLVGALSESK EQEFGKLFSK YLADPSNLFV VSSDFCHWGQ RFRYSYYDES QGEIYRSIEH LDKMGMSIIE QLDPVSFSNY LKKYHNTICG RHPIGVLLNA ITELQKNGMN MSFSFLNYAQ SSQCRNWQDS SVSYAAGALT VH
Molecular weight:
(322aa), confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer, pH8.0, 50% glycerol, 5mM DTT, 300mM NaCl, 2mM EDTA
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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