Product Description for Nucleophosmin
Nucleophosmin.
Presentation: Purified
Presentation: Purified
Properties for Nucleophosmin
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | NPM, NPM1, Nucleolar Phosphoprotein B23, Nucleolar Protein NO38, Numatrin |
| Presentation | Purified |
| Molecular weight | 34.7 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | NPM1 is a phosphoprotein which moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in NPM1 are associated with acute myeloid leukemia. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Sagawa,F., et al. (2011) EMBO J. 30 (19), 3994-4005.Neubauer,A., et al. (2011) Exp. Hematol. 39 (10), 1030-1042. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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