Product Description for MYL12B
MYL12B.
Presentation: Purified
Presentation: Purified
Properties for MYL12B
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | MLC-2, MLC-2A, MLC20, MRLC2, MYLC2B, Myosin regulatory light chain 2-B, Myosin regulatory light chain 20 kDa, Myosin regulatory light chain MRLC2, SHUJUN-1, smooth muscle isoform |
| Presentation | Purified |
| Molecular weight | 22.3 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 90 % by SDS - PAGE |
| Background | Myosin, light chain 12B, regulatory, also known as MYL12B, is a hexameric ATPase cellular motor protein. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. MYL12B regulates contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases Actin-activated myosin ATPase activity, thereby regulating contractile activity. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Kumar C C., et al. (1989) Biochemistry. 28:4027-4035.Kolodney M S., et al. (1999) J Physiol. 515: 87-92. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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