Product Description for CKMT
CKMT.
Presentation: Purified
Presentation: Purified
Properties for CKMT
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | Acidic-type mitochondrial creatine kinase, CKMT1A, CKMT1B, Creatine kinase U, Mia-CK, U-MtCK, ubiquitous mitochondrial Creatine kinase |
| Presentation | Purified |
| Molecular weight | 45 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 95 % by SDS - PAGE |
| Background | Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Stachowiak O., et al. (1998). Mol. Cell. Biochem. 184 (1-2): 141-51. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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