CD274 / PDL1 (19-238, His-tag) - AR50367PU-N

Product Description for CD274 / PDL1

CD274 / PDL1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1
Presentation	Purified
Molecular weight	27.9 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9NZQ7
Purity	> 90 % by SDS - PAGE
Background	CD274, also known as programmed cell death 1 ligand 1(PDCD1L1), is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. This protein interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Dong H., et al. (1999) Nat. Med. 5:1365-1369. Freeman G.J., et al. (2000) J. Exp. Med. 192:1027-1034
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant Human CD274 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSHMFTVTV PKDLYVVEYG SNMTIECKFP VEKQLDLAAL IVYWEMEDKN IIQFVHGEED LKVQHSSYRQ RARLLKDQLS LGNAALQITD VKLQDAGVYR CMISYGGADY KRITVKVNAP YNKINQRILV VDPVTSEHEL TCQAEGYPKA EVIWTSSDHQ VLSGKTTTTN SKREEKLFNV TSTLRINTTT NEIFYCTFRR LDPEENHTAE LVIPELPLAH PPNER` Molecular weight: (245aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Format	Buffer System: 20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT Purity: >90% by SDS - PAGE State: Liquid purified protein Purified