Product Description for ZADH1
ZADH1.
Presentation: Purified
Presentation: Purified
Properties for ZADH1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | 15-oxoprostaglandin 13-reductase, PRG-2, PTGR2, Prostaglandin-reductase 2, Zinc-binding alcohol dehydrogenase domain-containing protein 1 |
| Presentation | Purified |
| Molecular weight | 41.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | PTGR2 belongs to the medium-chain dehydrogenase/reductase superfamily. PTGR2 catalyzes an NADPH-dependent reduction of the conjugated alpha,beta-unsaturated double bond of 15-keto-PGE(2), a key step in terminal inactivation of prostaglandins and suppression of PPARgamma-mediated adipocyte differentiation. Selective inhibition of PTGR2 may contribute to the improvement of insulin sensitivity with fewer side effects. |
| Concentration | 1mg/ml (determined by Bradford assay) |
| General Readings | Wu Y.H., et al. (2008) Structure 16:1714-1723Auld, D.S. et al. (2008) Cell. Mol. Life Sci. 65: 3961-3970. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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