AKAP7 alpha/beta (1-81, His-tag) - AR50351PU-N

Product Description for AKAP7 alpha/beta

AKAP7 alpha/beta.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.25 mg
Synonyms	A-kinase anchor protein 18, A-kinase anchor protein 7 isoforms alpha and beta, AKAP18, AKAP7, Protein kinase A-anchoring protein 7 isoforms alpha/beta
Presentation	Purified
Molecular weight	11.5 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: O43687
Purity	> 90 % by SDS - PAGE
Background	AKAP7 (A-kinase anchor protein 7 isoform gamma isoform alpha) , also known as AKAP18, belongs to the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAP 7 is expressed in brain, heart, lung, pancreas and skeletal muscle. AKAP 7 binds PKA to the plasma membrane, and permits functional coupling to the L-type calcium channel.
Concentration	1mg/ml (determined by Bradford assay)
General Readings	Trotter K.W., et al. (1999) J. Cell Biol. 147:1481-1492Klussmann, E., et al. (2001) Kidney Int. 60: 446-449.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human AKAP7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSHMGQLCC FPFSRDEGKI SEKNGGEPDD AELVRLSKRL VENAVLKAVQ QYLEETQNKN KPGEGSSVKT EAADQNGNDN ENNRK` Molecular weight: (105aa), confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer, pH8.0, 10% glycerol, 1mM DTT, 50mM NaCl Purity: >90% by SDS - PAGE State: Liquid purified protein Purified