BLOC-1 subunit 2 (1-142, His-tag) - AR50352PU-S

Product Description for BLOC-1 subunit 2

BLOC-1 subunit 2.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	BLOC1S2, BLOS2, Biogenesis of lysosome-related organelles complex 1 subunit 2, CEAP
Presentation	Purified
Molecular weight	18.5 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q6QNY1
Purity	> 85 % by SDS - PAGE
Background	BLOC1S2 (Biogenesis of lysosome-related organelles complex 1 subunit 2) belongs to the BLOC1S2 family. BLOC-1 or biogenesis of lysosome-related organelles complex 1 is a ubiquitously expressed multisubunit protein complex. BLOC-1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. This protein plays a role in cell proliferation.
Concentration	1mg/ml (determined by Bradford assay)
General Readings	Starcevic M., et al. (2004) J. Biol. Chem. 279:28393-28401Wang Z., et al. (2004) J. Mol. Biol. 343:71-82
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human BLOC1S2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSHMAAAAE GVLATRSDEP ARDDAAVETA EEAKEPAEAD ITELCRDMFS KMATYLTGEL TATSEDYKLL ENMNKLTSLK YLEMKDIAIN ISRNLKDLNQ KYAGLQPYLD QINVIEEQVA ALEQAAYKLD AYSKKLEAKY KKLEKR` Molecular weight: (166aa), confirmed by MALDI-TOF(Molecular weight on SDS-PAGE will appear higher)
Format	Buffer System: 20 mM Tris-HCl buffer, pH8.0, 10% glycerol, 1mM DTT, 50mM NaCl Purity: >85% by SDS - PAGE State: Liquid purified protein Purified