TXNL4A / DIM1 (1-142, His-tag) - AR50363PU-N

Product Description for TXNL4A / DIM1

TXNL4A / DIM1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.25 mg
Synonyms	DIM1 protein homolog, Spliceosomal U5 snRNP-specific 15 kDa protein, Thioredoxin-like U5 snRNP protein U5-15kD, Thioredoxin-like protein 4A
Presentation	Purified
Molecular weight	19.3 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P83876
Purity	> 95 % by SDS - PAGE
Background	Thioredoxin-like 4A, also known as TXNL4A, belongs to the Dim protein family. TXNL4A is a 142 amino acid protein that plays an essential role in pre-mRNA splicing. Due to a failure to express early zygotic transcripts, deletion of the gene encoding TXNL4A in Schizosaccharomyces pombe leads to embryonal lethality during gastrulation. Localized to the nucleus, TXNL4A interacts with hnRNP F, hnRNP H2, Cas-L and PQBP-1 to effect gene expression.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Zhang Y Z., et al. (1999) Physiol Genomics. 1:109-118.Zhang Y Z., et al. (2000) Gene. 257: 33-43.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human TXNL4A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSHMSYMLP HLHNGWQVDQ AILSEEDRVV VIRFGHDWDP TCMKMDEVLY SIAEKVKNFA VIYLVDITEV PDFNKMYELY DPCTVMFFFR NKHIMIDLGT GNNNKINWAM EDKQEMVDII ETVYRGARKG RGLVVSPKDY STKYRY` Molecular weight: (166aa), confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT Purity: >95% by SDS - PAGE State: Liquid purified protein Purified