AR50280PU-N Casein kinase II subunit alpha (1-391, His-tag)

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0.5 mg / €1,070.00
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Casein kinase II subunit alpha

Product Description for Casein kinase II subunit alpha

Casein kinase II subunit alpha.
Presentation: Purified

Properties for Casein kinase II subunit alpha

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms CK II alpha, CK2A1, CSNK2A1
Presentation Purified
Molecular weight 47.8 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P68400
Purity > 90 % by SDS - PAGE
Background CSNK2A1, also known as casein kinase II subunit alpha, are catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. It regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. CSNK2A1 may act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Prudent R., et al. (2010) Cancer Res. 70:9865-9874Deloukas P., et al. (2001) Nature. 414:865-871
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human CSNK2A1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMMSGPV PSRARVYTDV NTHRPREYWD YESHVVEWGN QDDYQLVRKL GRGKYSEVFE AINITNNEKV VVKILKPVKK KKIKREIKIL ENLRGGPNII TLADIVKDPV SRTPALVFEH VNNTDFKQLY QTLTDYDIRF YMYEILKALD YCHSMGIMHR DVKPHNVMID HEHRKLRLID WGLAEFYHPG QEYNVRVASR YFKGPELLVD YQMYDYSLDM WSLGCMLASM IFRKEPFFHG HDNYDQLVRI AKVLGTEDLY DYIDKYNIEL DPRFNDILGR HSRKRWERFV HSENQHLVSP EALDFLDKLL RYDHQSRLTA REAMEHPYFY TVVKDQARMG SSSMPGGSTP VSSANMMSGI SSVPTPSPLG PLAGSPVIAA ANPLGMPVPA AAGAQQ
Molecular weight:
(416aa), confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT, 0.1mM PMSF
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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