Product Description for ARHGDIB / D4-GDI
ARHGDIB / D4-GDI.
Presentation: Purified
Presentation: Purified
Properties for ARHGDIB / D4-GDI
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 10 µg |
| Synonyms | GDIA2, GDID4, Ly-GDI, RAP1GN1, Rho GDI 2, Rho GDP-dissociation inhibitor 2, Rho-GDI beta, RhoGDI2 |
| Presentation | Purified |
| Molecular weight | 49.4 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 90 % by SDS - PAGE |
| Background | Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Skalnikova,H. et al. (2011) J. Proteome Res. 10 (2), 404-415Mehta,P. et al. (2011) PLoS ONE 6 (6), E21175 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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