AR50238PU-S Pirin / PIR (1-290, His-tag)

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0.1 mg / €320.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Pirin / PIR

Product Description for Pirin / PIR

Pirin / PIR.
Presentation: Purified

Properties for Pirin / PIR

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms 3-dioxygenase PIR, Probable quercetin 2, Probable quercetinase
Presentation Purified
Molecular weight 34.3 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O00625
Purity > 95 % by SDS - PAGE
Background PIR, also known as pirin, is a member of the cupin superfamily. PIR is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Gelbman B.D., et al. (2007) Respir. Res. 8:10-10Licciulli S., et al. (2010) Leukemia. 24:429-437
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human PIR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSSKKVTLS VLSREQSEGV GARVRRSIGR PELKNLDPFL LFDEFKGGRP GGFPDHPHRG FETVSYLLEG GSMAHEDFCG HTGKMNPGDL QWMTAGRGIL HAEMPCSEEP AHGLQLWVNL RSSEKMVEPQ YQELKSEEIP KPSKDGVTVA VISGEALGIK SKVYTRTPTL YLDFKLDPGA KHSQPIPKGW TSFIYTISGD VYIGPDDAQQ KIEPHHTAVL GEGDSVQVEN KDPKRSHFVL IAGEPLREPV IQHGPFVMNT NEEISQAILD FRNAKNGFER AKTWKSKIGN
Molecular weight:
(310aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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