Product Description for VPS25
VPS25.
Presentation: Purified
Presentation: Purified
Properties for VPS25
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | DERP9, Dermal papilla-derived protein 9, EAP20, ELL-associated protein of 20 kDa, ESCRT-II complex subunit VPS25, Vacuolar protein-sorting-associated protein 25 |
| Presentation | Purified |
| Molecular weight | 23.3 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | VPS25, also known as vacuolar protein-sorting-associated protein 25, consists of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may play a role in transcription regulation, possibly via its interaction with ELL. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Bailey,S.D. et al. (2010) Diabetes Care 33 (10), 2250-2253Talmud,P.J. et al. (2009) Am. J. Hum. Genet. 85 (5), 628-642 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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