AR50263PU-N Glycine amidinotransferase (38-423, His-tag)

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0.25 mg / €1,070.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Glycine amidinotransferase

Product Description for Glycine amidinotransferase

Glycine amidinotransferase.
Presentation: Purified

Properties for Glycine amidinotransferase

Product Category Proteins & Growth Factors
Quantity 0.25 mg
Synonyms AGAT, GATM, L-arginine:glycine amidinotransferase, Transamidinase
Presentation Purified
Molecular weight 46.9 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P50440
Purity > 90 % by SDS - PAGE
Background GATM (Glycine amidinotransferase, mitochondrial) is a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. It plays a role in embryonic and central nervous system development.
Concentration 1mg/ml (determined by Bradford assay)
General Readings Schulze A (2003). Mol. Cell. Biochem. 244 (1-2): 143-50.Cullen M.E., Et al. (2006) Circulation 114:I16-I20
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human GATM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMSTQAAT ASSRNSCAAD DKATEPLPKD CPVSSYNEWD PLEEVIVGRA ENACVPPFTI EVKANTYEKY WPFYQKQGGH YFPKDHLKKA VAEIEEMCNI LKTEGVTVRR PDPIDWSLKY KTPDFESTGL YSAMPRDILI VVGNEIIEAP MAWRSRFFEY RAYRSIIKDY FHRGAKWTTA PKPTMADELY NQDYPIHSVE DRHKLAAQGK FVTTEFEPCF DAADFIRAGR DIFAQRSQVT NYLGIEWMRR HLAPDYRVHI ISFKDPNPMH IDATFNIIGP GIVLSNPDRP CHQIDLFKKA GWTIITPPTP IIPDDHPLWM SSKWLSMNVL MLDEKRVMVD ANEVPIQKMF EKLGITTIKV NIRNANSLGG GFHCWTCDVR RRGTLQSYLD
Molecular weight:
(410aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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