AR50254PU-S Glutathione peroxidase 3 / GPX3 (21-226, His-tag)

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50 µg / €400.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Glutathione peroxidase 3 / GPX3

Product Description for Glutathione peroxidase 3 / GPX3

Glutathione peroxidase 3 / GPX3.
Presentation: Purified

Properties for Glutathione peroxidase 3 / GPX3

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms Extracellular glutathione peroxidase, GPX-3, GPXP, GPx-3, GPx-P, GSHPXP, GSHPx-3, GSHPx-P, Glutathione peroxidase-3, Plasma glutathione peroxidase
Presentation Purified
Molecular weight 25.7 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P22352
Purity > 90 % by SDS - PAGE
Background GPX3, also known as glutathione peroxidase 3, belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. GPX3 protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA.
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings
  • Esworthy R.S., et al. (1991) Arch. Biochem. Biophys. 286:330-336
  • Comhair S.A.A., et al. (2000) Am. J. Respir. Cell Mol. Biol. 23:350-354
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human GPX3(U73C) protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MQSRGQEKSK MDCHGGISGT IYEYGALTID GEEYIPFKQY AGKYVLFVNV ASYCGLTGQY IELNALQEEL APFGLVILGF PCNQFGKQEP GENSEILPTL KYVRPGGGFV PNFQLFEKGD VNGEKEQKFY TFLKNSCPPT SELLGTSDRL FWEPMKVHDI RWNFEKFLVG PDGIPIMRWH HRTTVSNVKM DILSYMRRQA ALGVKRK
Molecular weight:
(227aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT,50mM Imodazol
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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