Product Description for Gamma-glutamyl hydrolase / GGH
Gamma-glutamyl hydrolase / GGH.
Presentation: Purified
Presentation: Purified
Properties for Gamma-glutamyl hydrolase / GGH
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | Conjugase, GH, Gamma-Glu-X carboxypeptidase |
| Presentation | Purified |
| Molecular weight | 35.9 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 95 % by SDS - PAGE |
| Background | Gamma-glutamyl hydrolase, also known as GGH, is a homodimeric protein that catalyzes the cleavage of the gamma-glutamyl chain of folylpoly-gamma-glutamyl substrates and is a central enzyme in folyl and antifolyl poly-gamma-glutamate metabolism. GGH may play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Rhee M S., et al. (1998) Mol Pharmacol. 53:1040-1046.Galivan J., et al. (1999) Semin Oncol. 26:33-37. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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