Product Description for Serine racemase / SRR
Serine racemase / SRR.
Presentation: Purified
Presentation: Purified
Properties for Serine racemase / SRR
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 50 µg |
| Presentation | Purified |
| Molecular weight | 39.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | SRR, also known as serine racemase, is an enzyme which generates D-serine from L-serine. D-serine acts as a neuronal signaling molecule by activating NMDA receptors in the brain. Mammalian serine racemase is a pyridoxal 5'-phosphate dependent enzyme that catalyzes both the racemization of L-serine to D-serine and also the elimination of water from L-serine, generating pyruvate and ammonia. The enzyme is physiologically stimulated by divalent cations (e.g., magnesium) and is allosterically activated by the magnesium/ATP complex. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | De Miranda J., et al. (2000) Gene. 256:183-188Smith M.A., et al. (2010) J. Biol. Chem. 285:12873-12881 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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