Product Description for PTPMT1
PTPMT1.
Presentation: Purified
Presentation: Purified
Properties for PTPMT1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | MOSP, PLIP, PNAS-129, PTEN-like phosphatase, Phosphoinositide lipid phosphatase, Protein-tyrosine phosphatase mitochondrial 1 |
| Presentation | Purified |
| Molecular weight | 22.6 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 95 % by SDS - PAGE |
| Background | PTPMT1 (protein tyrosine phosphatase mitochondrial 1), also known as MOSP or PLIP (phosphoinositide lipid phosphatase) and previously known as DUSP23, is a widely expressed PTP membrane protein with high expression levels in pancreatic beta cells. This protein exclusively localizes to the matrix face of the inner membrane of the mitochondrion. It is responsible for dephosphorylating mitochondrial proteins and therefore plays a significant role in the production of ATP and secretion of insulin. For its substrate, PTPMT1 displays a specific preference for the lipid signaling molecule phosphatidylinositol 5-phosphate. |
| Concentration | 1 mg/ml (determined by Bradford) |
| General Readings | Pagliarini DJ., et al. (2005) Mol Cell. 19(2):197-207.Merlot S., et al. (2003) J Biol Chem. 278(41):39866-73. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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