XTP3TPA / DCTPP1 (1-170, His-tag) - AR50206PU-S

Product Description for XTP3TPA / DCTPP1

XTP3TPA / DCTPP1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	50 µg
Synonyms	CDA03, Deoxycytidine-triphosphatase 1, RS21-C6, RS21C6, XTP3-transactivated gene A protein, dCTP pyrophosphatase 1, dCTPase 1
Presentation	Purified
Molecular weight	21.2 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9H773
Purity	> 90 % by SDS - PAGE
Background	DCTPP1, also known as dCTP pyrophosphatase 1, contains an epilepsy-associated repeat (EAR) domain that is predicted to participate in protein-protein interactions, most likely involved in ligand recognition. This protein functions to hydrolyze abnormal nucleotide triphosphates (NTPs) in cancer cells that, if unregulated, could be incorporated into nascent DNA or RNA.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Moroz O.V. et al. (2005) J. Mol. Biol. 347: 243-255.Rual J.F. et al. (2005) Nature 437:1173-1178.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human DCTPP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSHMSVAGG EIRGDTGGED TAAPGRFSFS PEPTLEDIRR LHAEFAAERD WEQFHQPRNL LLALVGEVGE LAELFQWKTD GEPGPQGWSP RERAALQEEL SDVLIYLVAL AARCRVDLPL AVLSKMDINR RRYPAHLARS SSRKYTELPH GAISEDQAVG PADIPCDSTG QTST` Molecular weight: (194aa) confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl Purity: >90% by SDS - PAGE State: Liquid purified protein Purified