Product Description for Glutathione peroxidase 2 / GPX2
Glutathione peroxidase 2 / GPX2.
Presentation: Purified
Presentation: Purified
Properties for Glutathione peroxidase 2 / GPX2
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 50 µg |
| Synonyms | GPRP, GPx-2, GSHPx-2, Gastrointestinal glutathione peroxidase, Glutathione peroxidase-related protein 2 |
| Presentation | Purified |
| Molecular weight | 24.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 95 % by SDS - PAGE |
| Background | GPX2, also known as glutathione peroxidase 2, belongs to the glutathione peroxidase family, consisting of eight known glutathione peroxidases (Gpx1-8) in humans. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. GPX2 could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Chu F.-F., et al. (1993) J. Biol. Chem. 268:2571-2576Kelner M.J., et al. (2000) Gene. 248:109-116 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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