AR50151PU-N DHRS4 (1-278, His-tag)

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50 µg / €820.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

DHRS4

Product Description for DHRS4

DHRS4.
Presentation: Purified

Properties for DHRS4

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms Dehydrogenase/reductase SDR family member 4, NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase, NADPH-dependent retinol dehydrogenase/reductase, NRDR, PHCR, PSCD, Peroxisomal short-chain alcohol dehydrogenase, SCAD-SRL, Short-chain dehydrogenase/reductase family member 4
Presentation Purified
Molecular weight 32.1 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9BTZ2
Purity > 85 % by SDS - PAGE
Background DHRS4, also known as dehydrogenase/reductase SDR family member 4, belongs to the short-chain dehydrogenases/reductases (SDR) family. DHRS4 reduces all trans retinal and 9 cis retinal. This protein can also catalyze the oxidation of all trans retinol with NADP as cofactor, but with much lower efficiency. Also, DHRS4 reduces alkyl phenyl ketones and alpha dicarbonyl compounds with aromatic rings, such as pyrimidine 4 aldehyde, 3 benzoylpyridine, 4 benzoylpyridine, menadione and 4 hexanoylpyridine.
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings Fransen M., et al. (1999) Biochem. J. 340:561-568Du J., et al. (2004) Yi Chuan Xue Bao. 31:661-667
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human DHRS4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMHKAGL LGLCARAWNS VRMASSGMTR RDPLANKVAL VTASTDGIGF AIARRLAQDG AHVVVSSRKQ QNVDQAVATL QGEGLSVTGT VCHVGKAEDR ERLVATAVKL HGGIDILVSN AAVNPFFGSI MDVTEEVWDK TLDINVKAPA LMTKAVVPEM EKRGGGSVVI VSSIAAFSPS PGFSPYNVSK TALLGLTKTL AIELAPRNIR VNCLAPGLIK TSFSRMLWMD KEKEESMKET LRIRRLGEPE DCAGIVSFLC SEDASYITGE TVVVGGGTPS RL
Molecular weight:
(302aa), confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH7.5) containing 20% glycerol, 1mM DTT
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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