GADD45GIP1 (48-222, His-tag) - AR50105PU-N

Product Description for GADD45GIP1

GADD45GIP1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.25 mg
Synonyms	CKII beta-associating protein, CR6-interacting factor 1, CRIF1, Growth arrest and DNA-damage-inducible proteins-interacting protein 1, PLINP1, PRG6, Papillomavirus L2-interacting nuclear protein 1, p53-responsive gene 6 protein
Presentation	Purified
Molecular weight	22.6 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q8TAE8
Purity	> 90 % by SDS - PAGE
Background	GADD45GIP1, also known as CRIF1, is a nuclear protein that plays a role in apoptosis control. This protein is expressed in a variety of tissues, including heart, thyroid, trachea, kidney, ovary, pancreas, testis and stomach. It functions as a negative regulator of G1 to S phase cell cycle production, specifically by working with GADD45 proteins to inhibit the activity of cyclin-dependent kinases.
Concentration	0.25 mg/ml (determined by Bradford)
General Readings	Chung HK., et al. (2003) J Biol Chem. 278(30):28079-88.Park KC., et al. (2005) Mol Endocrinol. 19(1):12-24.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human GADD45GIP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MPRWQLGPRY AAKQFARYGA ASGVVPGSLW PSPEQLRELE AEEREWYPSL ATMQESLRVK QLAEEQKRRE REQHIAECMA KMPQMIVNWQ QQQRENWEKA QADKERRARL QAEAQELLGY QVDPRSARFQ ELLQDLEKKE RKRLKEEKQK RKKEARAAAL AAAVAQDPAA SGAPSS` Molecular weight: (196aa), confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer(pH 8.0) containing 40% glycerol, 2mM DTT, 0.2M NaCl. Purity: >90% by SDS - PAGE State: Liquid purified protein Purified