Product Description for GMDS
GMDS.
Presentation: Purified
Presentation: Purified
Properties for GMDS
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | 6 dehydratase, GDP-D-mannose dehydratase, GDP-mannose 4, GMD |
| Presentation | Purified |
| Molecular weight | 44.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 95 % by SDS - PAGE |
| Background | GMDS, also known as SDR3E1, belongs to the GDP-mannose 4,6-dehydratase family. This protein utilizes NADP as a cofactor to catalyze the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose. Mutations in the gene encoding GMDS are involved in resistance to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Ohyama C. et al. (1998) J Biol Chem. 273: 14582-14587.Moriwaki K. et al. (2009) Gastroenterology 137: 188-198. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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