Product Description for SGK1 / SGK
SGK1 / SGK.
Presentation: Purified
Presentation: Purified
Properties for SGK1 / SGK
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 50 µg |
| Synonyms | Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1 |
| Presentation | Purified |
| Molecular weight | 44.5 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | SGK1, also known as serum-and glucocorticoid-regulated kinase, is a serine/threonine protein kinase and a member of the “AGC” subfamily, which includes protein kinases A, G, and C. This protein plays an important role in activating certain potassium, sodium and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. It is activated in vitroby 3-phosphoinositide-dependent protein kinase-1 (PDK-1) and in vivoin response to signals that activate phosphatidylinositol (PI) 3-kinase. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Maiyar A.C. et al. (1996) J. Biol. Chem.. 271: 12414-12422.Brunet A. et al. (2001) Mol. Cell. Biol. 21:952-65 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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