MYCBP (1-103, His-tag) - AR50051PU-N

Product Description for MYCBP

MYCBP.
Presentation: Purified

Immunogen	Swiss Prot Num: Q99417
Purity	> 95 % by SDS - PAGE
Background	MYCBP, also known as c-Myc binding protein, binds to the transactivation domain of c-Myc and stimulates the activation of E-box-dependent transcription. It translocates from the cytoplasm to the nucleus during S phase when increased expression of c-Myc occurs. It has also been shown to associate with AKAP 149 and AKAP 84 in mitochondria of somatic cells and sperm, which suggests a role for MYCBP in spermatogenesis.
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Furusawa M. et al. (2001) J. Biol. Chem. 276: 36647-36651.Yukitake H. et al. (2002) J. Biol. Chem. 277: 45480-45492.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human MYCBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MAHYKAADSK REQFRRYLEK SGVLDTLTKV LVALYEEPEK PNSALDFLKH HLGAATPENP EIELLRLELA EMKEKYEAIV EENKKLKAKL AQYEPPQEEK RAE` Molecular weight: (123aa), confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT Purity: >95% by SDS - PAGE State: Liquid purified protein Purified