RAB35 / RAB1C (1-203, His-tag) - AR50043PU-S

Product Description for RAB35 / RAB1C

RAB35 / RAB1C.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	50 µg
Synonyms	GTP-binding protein RAY, RAY, Rab-1C, Rab-35, Ras-related protein Rab-1C, Ras-related protein Rab-35
Presentation	Purified
Molecular weight	25.2 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q15286
Purity	> 90 % by SDS - PAGE
Background	RAB35, also known as ras-related protein Rab-35, is localized to the plasma membrane and endocytic compartments and controls a fast endocytic recycling pathway. Consistent with a key requirement for Rab35-regulated recycling during cell division, inhibition of Rab35 function leads to the accumulation of endocytic markers on numerous cytoplasmic vacuoles in cells that failed cytokinesis.
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Kouranti I., et al. (2006) Curr. Biol. 16:1719-1725Marat A.L., et al. (2010) J. Biol. Chem. 285:10627-10637
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human RAB35 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MARDYDHLFK LLIIGDSGVG KSSLLLRFAD NTFSGSYITT IGVDFKIRTV EINGEKVKLQ IWDTAGQERF RTITSTYYRG THGVIVVYDV TSAESFVNVK RWLHEINQNC DDVCRILVGN KNDDPERKVV ETEDAYKFAG QMGIQLFETS AKENVNVEEM FNCITELVLR AKKDNLAKQQ QQQQNDVVKL TKNSKRKKRC C` Molecular weight: (221aa), confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT Purity: >90% by SDS - PAGE State: Liquid purified protein Purified