AR50044PU-N ARL14 / ARF7 (1-192, His-tag)

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0.5 mg / €820.00
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ARL14 / ARF7

Product Description for ARL14 / ARF7

ARL14 / ARF7.
Presentation: Purified

Properties for ARL14 / ARF7

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms ADP-ribosylation factor 7, ADP-ribosylation factor-like protein 14
Presentation Purified
Molecular weight 23.8 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q8N4G2
Purity > 90 % by SDS - PAGE
Background ARL14 (ADP-ribosylation factor-like 14) is a developmentally regulated member of the ADP-ribosylation factor/ARF-like protein (ARF/ARL) family of Ras-related GTPases. MHC class II molecules (MHC-II) present peptides to T helper cells to facilitate immune responses and are strongly linked to autoimmune diseases. MHC-II transport was controlled by the GTPase ARL14/ARF7, which recruits the motor myosin 1E via an effector protein ARF7EP.
Concentration 0.25mg/ml (determined by Bradford assay)
General Readings Paul P, et al. (2011) Cell. 145(2):268-83.Imami K., et al. (2008) Anal. Sci. 24:161-166
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human ARL14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSLGSKNPQ TKQAQVLLLG LDSAGKSTLL YKLKLAKDIT TIPTIGFNVE MIELERNLSL TVWDVGGQEK MRTVWGCYCE NTDGLVYVVD STDKQRLEES QRQFEHILKN EHIKNVPVVL LANKQDMPGA LTAEDITRMF KVKKLCSDRN WYVQPCCALT GEGLAQGFRK LTGFVKSHMK SRGDTLAFFK QN
Molecular weight:
(212aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 40% glycerol, 200mM NaCl, 1mM EDTA
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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